Figure 1

Map of group A and B KIR haplotypes. Distinct KIR haplotypes carry quantitively and qualitatively contrasting KIR gene content. Inhibitory KIR genes are depicted in white boxes. Activating KIRs are shown in dark boxes. Gray boxes represent pseudogenes or KIR genes with unclear function. HLA class I ligands for specific KIR are identified in dotted boxes. The centromeric and telomeric half are marked.