Figure 4
From: Sustained high expression of multiple APOBEC3 cytidine deaminases in systemic lupus erythematosus
Prevalence of the TERT rs2853669 polymorphism in SLE patients. (A) Prevalence of the TERT promoter rs2853669 A/G alleles in SLE patients and controls. The number of GGAA sites at position − 245 from the TSS was assessed from the TERT promoter reads. (B) Prevalence of TERT promoter rs2853669 A/G alleles in SLE patients stratified according to serum IFN-α levels. Full black circles represent patients heterozygous for the A3AΔ3B deletion. (C) and (D) A3A (C) and A3B (D) expression levels in SLE patients based on rs2853669 G/A polymorphism. Full symbols are SLE patients and black open symbols are controls. *p < 0.05; **p < 0.01; ***p < 0.001.
