Figure 3

HRM findings of swallow-induced LES relaxation, and LES accommodation in EGJOO and achalasia. (a, b) The series of representative HRM recordings in a patient with EGJOO (a) and a patient with achalasia (b). Red arrows indicate the swallowing action, while orange arrows indicate the action of injecting water into the oral cavity. (c,d) Cumulative data on swallow-induced LES relaxation in a total of five swallows in a patient with EGJOO and a patient with achalasia (c) and in each swallow in a patient with EGJOO (d) and a patient with achalasia (e), from the 1st to 5th wallows. (f–h) Cumulative data on LES accommodation in a total of five swallows in a patient with EGJOO and a patient with achalasia (f) and in each swallow in a patient with EGJOO (g) and a patient with achalasia (h), from the 1st to 5th swallows. (i) Cumulative data of receptive LES relaxation in a total of five swallows in a patient with EGJOO. Data are shown as the median (interquartile range). A one-way ANOVA followed by Turkey’s multiple comparison test was conducted (c and f) and an unpaired t-test was conducted (i). *A statistically significant difference between the two indicated groups. n.s., no significant difference between the two indicated groups. A repeated measure analysis of variance followed by Dunnett’s test was conducted (d, e, g, h), with the value of the 1st swallow (sw1) set as the control. n.s., no significant difference vs. sw1.