Table 6 Comparison of the craniocervical junction abnormalities between genetic skeletal disorder patients with and without CNS injury.
Craniocervical junction abnormalities | CNS injury n (%) | No CNS injury n (%) | p* | OR (95% CI) |
|---|---|---|---|---|
Os odontoideum | 11/71 (15.5) | 9/201 (4.5) | 0.006 | 4.2 (1.4–11.1) |
Basilar impression/invagination | 15/71 (21.1) | 20/201 (10.0) | 0.016 | 2.4 (1.1–5.3) |
Narrowed foramen magnum | 14/71 (19.7) | 20/201 (10.0) | 0.032 | 2.2 (1.0–5.0) |
Spinal canal stenosis at C2 | 59/71 (83.1) | 155/201 (77.1) | 0.290 | 1.5 (0.7–3.2) |
Atlanto-odontoid instability | 6/71 (8.5) | 10/201 (5.0) | 0.377 | 1.8 (0.5–5.6) |
Cervical spinal cord compression | 17/71 (23.9) | 41/201 (20.4) | 0.531 | 1.2 (0.6–2.4) |
Atlanto-occipital instability | 3/71 (4.2) | 6/201 (3.0) | 0.701 | 1.4 (0.2–6.9) |
Basio-occipital hypoplasia | 41/71 (57.7) | 127/201 (60.7) | 0.768 | 0.9 (0.5–1.6) |
Terminal bone at C2 | 2/71 (2.8) | 4/201 (2.0) | 1.000 | 0.9 (0.1–5.4) |
Platybasia | 1/71 (1.4) | 4/201 (2.0) | 1.000 | 0.7 (0.1–7.3) |
