Table 7 Comparison of radiological spinal abnormalities between genetic skeletal disorder patients with and without CNS injury.

From: Identification of clinical and radiographic predictors of central nervous system injury in genetic skeletal disorders

Radiological spinal abnormalities

CNS injury

n (%)

No CNS injury

n (%)

p*

OR

(95% CI)

Platyspondyly

18/71 (25.4)

26/201 (12.9)

0.015

2.3 (1.1–4.7)

Cervical platyspondyly

16/71 (22.5)

19/201 (9.5)

0.005

2.8 (1.2–6.1)

Thoracic platyspondyly

18/71 (25.4)

23/201 (11.4)

0.005

2.6 (1.2–5.5)

Lumbar platyspondyly

18/71 (25.4)

21/201 (10.4)

0.002

2.9 (1.3–6.2)

Thoracolumbar kiphosis

15/71 (21.1)

25/201 (12.4)

0.076

1.9 (0.9–4.0)

Scoliosis

36/71 (50.7)

122/201 (60.7)

0.142

0.7 (0.4–1.2)

Osteochondrosis intervertebral

46/71 (64.8)

113/201 (56.2)

0.208

1.4 (0.8–2.6)

Cervical osteochondrosis

36/71 (50.7)

82/201 (40.8)

0.148

1.5 (0.8–2.7)

Thoracic osteochondrosis

28/71 (39.4)

50/201 (24.9)

0.020

2.0 (1.1–3.6)

Lumbar osteochondrosis

24/71 (33.8)

57/201 (28.4)

0.389

1.3 (0.7–2.4)

Spinal vertebrae compression

11/71 (15.5)

39/201 (19.4)

0.465

0.8 (0.3–1.6)

Cervical compression

0/71 (0.0)

4/201 (2.0)

0.558

0.0 (0.0–4.3)

Thoracic compression

10/71 (14.1)

35/201 (17.4)

0.516

0.8 (0.3–1.7)

Lumbar compression

5/71 (7.0)

17/201 (8.5)

0.805

0.8 (0.2–2.4)

Spinal canal stenosis

31/71 (43.7)

79/201 (39.3)

0.520

1.2 (0.7–2.1)

Cervical stenosis

24/71 (33.8)

57/201 (28.4)

0.389

1.3 (0.7–2.4)

Thoracic stenosis

17/71 (23.9)

37/201 (18.4)

0.315

1.4 (0.7–2.8)

Lumbar stenosis

12/71 (16.9)

35/201 (17.4)

0.922

1.0 (0.4–2.1)

  1. CNS central nervous system, OR odds ratio, CI confidence interval.
  2. *X2 test or Fisher’s exact test.