Figure 3 | Scientific Reports

Figure 3

From: A 3-month-delayed treatment with anatabine improves chronic outcomes in two different models of repetitive mild traumatic brain injury in hTau mice

Figure 3

Evaluation of the effect of TBI and of anatabine on motor performance. (A) 24r-mTBI-vehicle mice exhibited a decrease in latency over the 7-day period compared to 24r-Sham-Vehicle controls (p < 0.0001). Treatment with anatabine in 24r-mTBI mice increased latency from Day1 to Day7 (p < 0.0001). (B) 5r-mTBI-Vehicle mice exhibited a decreased latency compared to 5r-Sham-Vehicle on Day1 and Day 3 but not on Day5 and Day7. Mice of 5r-mTBI-Anatabine group had no difference in latency compared to 5r-mTBI-Vehicle mice (p > 0.05). All data were normalized to baseline and analyzed using MANOVA.

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