Figure 8

Evaluation of the effect of anatabine on RZ3 (Thr231) in cortex. (A) Representative images of RZ3 (Thr231) in cortex. TBI induced an increase of RZ3 (Thr231) in both 5r-mTBI ((B), p < 0.05) and 24r-mTBI ((C), p < 0.001) mice compared to the respective sham-vehicle. In anatabine treated mice, RZ3 (Thr231) was decreased in both 5r-mTBI (p < 0.05) and 24r-mTBI (p < 0.001) mice compared to the respective r-mTBI-vehicle. Data analyzed using two-way ANOVA. Scale bars equal 20 µm.