Figure 5
From: Post-synthesis nanostructuration of BSA-Capsaicin nanoparticles generated by sucrose excipient
(a) Effective diameter parameter of isolated BSA-capsaicin nanoparticles versus capsaicin concentration for different drying procedures. The DS treatment showed a protective effect that allowed to reduce the size of nanoparticles at a high concentration of capsaicin. (b) The isolated nanoparticles showed a gradual loss of shape compared with NPs without drying (ND) treatment as a function of initial capsaicin concentration. DW and DN treatments did not show protective effect in any formulation. DS showed a protective effect and increase of the circular shape (Sf = 1). The equation of shape factor (Sf) is also displayed. (c) Aspect ratio of BSA-nanoparticles versus capsaicin concentration. ND treatment resulted in a gradual transition from circular to ellipsoidal shape. DW and DN did not show a protective effect in all formulations. The NS treatment showed a protective effect that reduced the change to elliptical shape at a high concentration of capsaicin (3250 μg mL−1). Values are means of three experimental replicates ± standard deviations.
