Figure 6
From: Post-synthesis nanostructuration of BSA-Capsaicin nanoparticles generated by sucrose excipient
(a) The ζ-potential of BSA-capsaicin nanoparticles showed an increase in the electronegativity associated with drying treatments. ND, DW, and DN treatments showed a negative effect, at 3250 µg mL−1 the saturation of capsaicin produces a significant increment of the ζ-potential. While the DS treatment showed a low increase of electronegativity due to the controlled reorganization of the amino acids and capsaicin molecules on the surface of nanoparticles. (b) The size of the aggregates of BSA-capsaicin nanoparticles showed an oscillatory behavior associated with drying treatments. Not drying (ND), dried with water (DW) and dried with NaCl (DN) treatments showed a negative effect. In all treatments 812 µg mL−1 of capsaicin produces a significant increment of the size of aggregates. The treatment dried with sucrose (DS) showed a protective effect and reduce the increment of size. Values are means of three experimental replicates ± standard deviations.
