Figure 3
From: Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses
Inhibition of SARS-CoV-2 entry by TPNT1. (a) Schematic illustration of the (pretreat + infection), infection-only, and post-infection experiments delineates the stage where TPNT1 was added to the viruses or the cells; (b) Quantification of the viral RNA in the supernatants of SARS-CoV-2 infected Vero E6 cells; (c) qRT-PCR detection of viral RNA in the SARS-CoV-2 infected Vero E6 cells ; (d) Western blot of the viral nucleocapsid (NP) protein; and (e) Immunofluorescence assay for the detection of SARS-CoV-2 NP probed with a rabbit monoclonal antibody. Scale bars: 100 µm. At least three independent experiments were performed and one representative result was shown. P < 0.05*; P < 0.001*** Full-length blots/gels of (d) were presented in Supplementary Fig. 2.
