Figure 5
From: Nanoparticle composite TPNT1 is effective against SARS-CoV-2 and influenza viruses

The antiviral activities of TPNT1 against influenza viruses in vitro. MDCK cells were incubated with (a) WSN (H1N1), (b) oseltamivir-resistant WSN (H1N1)(H274Y), (c) NIBRG14 (H5N1), and (d) oseltamivir-resistant NIBRG14 (H5N1)(H274Y) at various viral inputs in the presence of TPNT1. After 48 h at 35 °C, the virus-induced cytotoxicity was monitored. The cells incubated with virus only were defined as 0% while the cells with no virus inoculation were defined as 100% inhibition.