Table 3 The clinical, demographic, and behavioral data according to AK classification.

From: A hospital-based study on clinical data, demographic data and visual function of keratoconus patients in Central China

Parameters

AK1 (N = 124)

AK2 (N = 137)

AK3 (N = 109)

AK4 (N = 154)

F/χ2

P#

r

P*

Clinical data

TCT (µm)

482.92 ± 33.92 (419, 592)

464.83 ± 33.92 (395, 568)

450.68 ± 40.16 (369, 563)

402.03 ± 55.30 (237, 534)

65.442

< 0.001

− 0.52

< 0.001

Km (D)

44.93 ± 1.62 (40.9, 47.9)

47.86 ± 2.83 (39.8, 52.7)

50.37 ± 3.28 (43.0, 54.9)

58.83 ± 6.12 (45.1, 77.0)

248.214

< 0.001

0.76

< 0.001

Ks (D)

46.14 ± 2.05 (41.6, 50.9)

49.97 ± 3.53 (43.2,58.6)

52.39 ± 3.74 (43.3, 59.8)

61.30 ± 6.85 (46.7, 84.2)

215.330

< 0.001

0.74

< 0.001

Kmax (D)

50.43 ± 4.69 (43.2, 65.6)

56.73 ± 6.77 (43.8, 93.9)

60.65 ± 7.61 (43.8, 78.5)

73.46 ± 10.13 (48.1, 92.5)

160.454

< 0.001

0.69

< 0.001

SP-A1 (mmHg/mm)

84.90 ± 18.45 (38.22, 128.83)

71.57 ± 19.93 (38.58, 135.18)

63.68 ± 20.39 (24.15, 123.75)

48.52 ± 20.78 (12.49, 131.18)

54.883

< 0.001

− 0.55

< 0.001

Demographic data

Enrollment age

23.02 ± 7.09 (12, 46)

22.69 ± 6.36 (12, 46)

22.25 ± 5.18 (13, 40)

23.48 ± 7.49 (13, 54)

0.796

0.496

0.02

0.665

Sex (M/F)

86/38

94/43

75/34

116/38

2.177

0.537

− 0.05

0.254

Behavioral data

Eye rubbing (no/yes)

47/77

47/90

38/71

47/106

1.601

0.659

0.05

0.238

Glasses (no/yes)

38/86

43/94

21/88

58/96

13.389

0.004

− 0.04

0.413

RGP lenses (no/yes)

80/44

68/69

41/68

77/77

12.939

0.005

0.11

0.010

CXL surgery (no/yes)

84/40

59/78

42/67

101/53

27.927

< 0.001

− 0.01

0.985

Keratoplasty (no/yes)

124/0

137/0

109/0

129/25

16.224

0.001

0.28

< 0.001

  1. TCT thinnest corneal thickness, Km mean keratometry, Ks steep keratometry, Kmax the maximum keratometry, SP-A1 stiffness parameter at the first applanation, RGP rigid gas permeable, CXL cross-linking.
  2. P#: the statistical value of the general linear model or Chi-squared test, P*: the statistical value of Spearman’s correlation analysis.