Table 3 Fold increase of cytokine expression in patients with neovascular AMD and geographic atrophy (GA) as compared controls for different stimulation conditions.
Neovascular AMD | P value | GA | P value | |
---|---|---|---|---|
Non-treated | ||||
TNF-α | 0.99 (0.56–1.76) | 0.98 | 1.28 (0.58–2.80) | 0.54 |
IL-6 | 1.29 (0.72–2.32) | 0.39 | 1.91 (0.90–4.04) | 0.093 |
IL-10 | 0.64 (0.32–1.28) | 0.21 | 1.03 (0.42–2.56) | 0.95 |
LPS-treated | ||||
TNF-α | 1.30 (0.71–2.39) | 0.40 | 1.24 (0.57–2.72) | 0.59 |
IL-6 | 1.13 (0.63–2.01) | 0.68 | 1.76 (0.75–4.13) | 0.20 |
IL-10 | 0.93 (0.53–1.65) | 0.81 | 0.74 (0.35–1.53) | 0.41 |
CML-treated | ||||
TNF-α | 0.81 (0.42–1.54) | 0.52 | 0.46 (0.20–1.06) | 0.068 |
IL-6 | 0.60 (0.30–1.20) | 0.15 | 0.77 (0.35–1.70) | 0.52 |
IL-10 | 0.63 (0.34–1.17) | 0.14 | 0.71 (0.32–1.55) | 0.39 |
A2E-treated | ||||
TNF-α | 1.41 (0.63–3.14) | 0.40 | 2.61 (1.00–6.83) | 0.051 |
IL-6 | 0.82 (0.45–1.48) | 0.51 | 0.97 (0.49–1.93) | 0.93 |
IL-10 | 1.31 (0.73–2.35) | 0.37 | 1.03 (0.49–2.19) | 0.94 |