Table 2 Risk estimation for treatment nonadherence for primary DM outcomes and study covariates through hierarchical multivariate logistic regression models on diabetic patients with comorbid depression (N = 3340).

From: The TELE-DD project on treatment nonadherence in the population with type 2 diabetes and comorbid depression

Study variables

Categories

Unadjusted

Model 1

Model 2

Model 3

OR

95% CI

 

OR

95% CI

 

OR

95% CI

 

OR

95% CI

 

Age

Increased score

1.00

0.99

1.01

1.00

0.99

1.01

1.00

0.99

1.01

1.00

0.99

1.01

Sex

Female

1.00

  

1.00

  

1.00

  

1.00

  

Male

1.13

0.97

1.31

1.16

0.98

1.36

1.12

0.95

1.33

1.12

0.94

1.32

Diabetes duration, years

Ref

1.00

     

1.00

  

1.00

  

Increased score

0.98*

0.97

0.99

   

0.98**

0.97

0.99

0.98**

0.96

0.99

Depression duration, years

Ref

1.00

     

1.00

  

1.00

  

Increased score

0.98

0.97

1.01

   

0.99

0.98

1.01

0.99

0.98

1.01

Nurse visits

Ref

1.00

     

1.00

  

1.00

  

Increased score

1.00

0.99

1.01

   

1.00

0.99

1.01

1.00

0.99

1.00

PCS visits

Ref

1.00

     

1.00

  

1.00

  

Increased score

1.01

1.00

1.02

   

1.01*

1.00

1.02

1.01*

1.00

1.02

Drug intake (#)

Ref

1.00

        

1.00

  

Increased score

1.00

0.98

1.03

      

0.99

0.96

1.02

Smoking Status

Ref

1.00

     

1.00

  

1.00

  

Current smoker

1.13

0.90

1.43

   

1.16

0.90

1.49

1.15

0.90

1.48

BMI

Ref

1.00

        

1.00

  

Increased score

0.99

0.98

1.01

      

0.99

0.97

1.00

Systolic Blood pressure

Ref

1.00

        

1.00

  

Increased score

1.00

0.99

1.01

      

1.00

0.99

1.01

Blood Diastolic pressure

Ref

1.00

        

1.00

  

Increased score

1.00

0.99

1.01

      

1.00

0.98

1.01

HbA1c

Ref

1.00

  

1.00

  

1.00

  

1.00

  

Increased score

1.39**

1.31

1.48

1.39**

1.32

1.48

1.42**

1.34

1.50

1.42**

1.34

1.51

LDL Cholesterol

Ref

1.00

  

1.00

  

1.00

  

1.00

  

Increased score

1.01**

1.01

1.01

1.01**

1.01

1.01

1.01**

1.01

1.01

1.01*

1.01

1.01

  1. Model 1 = Adjusted by age, gender, and primary DM outcomes (HbA1c and LDL Cholesterol).
  2. Model 2 = Model 1 + T2D duration (years), depression duration (years), nurse and PCS visits, and smoking status.
  3. Model 3 = Model 2 + # drug intake, BMI, systolic blood pressure, diastolic blood pressure.
  4. *p < .05; **p < .01.