Figure 5

Representative case showing the diffuse fluid at Segment 1/diffuse fluid with subretinal fluid at Segment 2 type of diabetic macular edema. (A–C) En face images of the retinal surface (A), Segment 1 (B), and Segment 2 (C) are presented. Epiretinal membrane (arrowheads in A) and associated retinal folds (arrows in A) can be observed at the surface of the retina. There is diffuse fluid with an area larger than the parafoveal area at both Segments 1 and 2 (arrowheads in B,C). Subretinal fluid, visualized as a high-intensity ring-shaped region, can also be observed at Segment 2 (arrows in C). (D–F) B-scan images and the green lines show the locations at which the en face images of the retinal surface (D), Segment 1 (E), and Segment 2 (F) were generated. The scan depth, indicated by the distance between the green line and green dotted line, was set to 0 μm for the en face image of the retinal surface (D) and 50 μm for the en face images of both Segments 1 and 2 (E,F, respectively). (G) A horizontal B-scan image centered at the fovea is presented. The fluid at Segment 1 is located at both Henle’s fiber layer (arrows in G) and the inner nuclear layer (dotted arrows in G). There is diffuse fluid at Segment 2 (asterisks in G). The X in (G) indicates subretinal fluid and the arrowhead in (G) shows that the posterior hyaloid is detached from the retina completely but remains attached to the optic disc.