Table 1 Clinical characteristics of the study population.

From: Circulating short and medium chain fatty acids are associated with normoalbuminuria in type 1 diabetes of long duration

 

Normoalbuminuria

(n = 99)

Albuminuria

(n = 209)

Age, years

39 ± 11

37 ± 8

Men, n (%)

41 (41%)

120 (57%)

Body mass index, kg/m2

25 ± 5

26 ± 5

Systolic blood pressure, mmHg

118 ± 12

129 ± 17

Diastolic blood pressure, mmHg

71 ± 7

78 ± 9

Type 1 Diabetes

100%

100%

Diabetes duration, years

24 ± 9

23 ± 9

HbA1c, %

8.8 ± 1.4

9.3 ± 1.7

ACR, mg/g creatinine

7 (5–10)

665 (393–1250)

eGFR, mL/min/1.73 m2

110 ± 14

97 ± 21

eGFR category: G1 (≥ 90 mL/min/1.73 m2), n (%)

91 (92%)

127 (61%)

eGFR category: G2 (60–< 90 mL/min/1.73 m2), n (%)

8 (8%)

82 (39%)

Cholesterol, mg/dL

180 ± 32

215 ± 48

HDL, mg/dL

57 ± 15

56 ± 17

ACE inhibitor/ARB use

19%

67%

Other antihypertensive treatment

8%

16%

Statin use

21%

19%

  1. Study subjects had long duration of Type 1 Diabetes, normal renal function, and persistent normoalbuminuria or a broad range of albuminuria.
  2. ACR albumin to creatinine ratio, HbA1c hemoglobin A1c, eGFR estimated glomerular filtration rate, HDL high density lipoprotein, ACE angiotensin-converting enzyme, ARB angiotensin II receptor blocker, n sample size. Continuous traits are presented as mean (± SD) or median (25th–75th percentile), and binary traits are presented as %. Classification of eGFR followed the guidelines set by NKF/KDIGO57.
Back to article page