Figure 5 | Scientific Reports

Figure 5

From: Activation of nuclear factor-kappa B by TNF promotes nucleus pulposus mineralization through inhibition of ANKH and ENPP1

Figure 5

Mineral content increased in IVD injected with TNAP/TNF transduced bNPs. (a) µCT image of rabbit discs injected with naïve and TNAP/TNF double-transduced cells; The tissue volume (TV), bone volume (BV) and new mineral formation (BV/TV) for the representative images are given in the table below the image; (b) new mineral formation in IVD injected with transduced cells assessed by µCT; the results presented as mean and standard error of all discs in a given group; (c) BV/TV of discs injected with transduced cells represented as a fold-change, compared to mean BV/TV in disc injected with naïve bNPs (n = 8/group).

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