Figure 2
(A) Qualitative change in total retinal blood flow according to changes in IOP from 15 to 75 mmHg, and the recovery state. The fine end of capillaries which made inter-capillary connections seemed to be more diminished than capillaries connected to arterioles and venules at 30 mmHg of IOP. At 45 mmHg, a dramatic decrease in capillary flow was observed. Only major cilioretinal vessels and peripapillary vessels showed flow signal above 60 mmHg. In the recovery state, all of the major vessels and capillary flows seemed to recover their signal intensity. (B) Structural OCT + OCTA B-scan cross section image shows flow signal (yellowish dot) on structural OCT. When the intraocular pressure rises to 45 mmHg, the lumen of the major retinal vessels started to collapse and the vascular lumen flattened; capillary flow decreases as pressure rise. However, the flow signal still appears to be present in the cilioretinal arteries until an IOP of 75 mmHg. In the choroidal circulation, as shown in the en-face OCT, the flow reduction was clearly seen at 45 mmHg, and almost no flow signal was observed above 60 mmHg.
