Figure 2
From: Modeling poliovirus replication dynamics from live time-lapse single-cell imaging data

Illustration of PV replication cycle and parameter estimation procedure. (A) The replication cycle of PV as represented in the model of Schulte et al.23. This figure is adapted from that work. Numbered steps correspond to individually modeled reactions given in Table 1. (B) Computational procedure to compare the output of the mechanistic model of a single PV infection to the experimental data obtained from populations of single-cell infections.