Figure 3 | Scientific Reports

Figure 3

From: Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr−/−.Leiden mice without attenuation of steatohepatitis

Figure 3

Fasting insulinemia vs glycemia with iso-HOMA-IR and iso-HOMA-%B curves at various timepoints (t) of the study (0, 8, 16, 24, and 32). Blue shadow zones represent the normality range for HOMA-%B (BETA 142 and BETA 91). Red shadow zones represent the normality range for HOMA-IR (HOMA 2.7 and HOMA 1.80). The normality ranges were established using fasting insulinemia and glycemia values at week 0 (t0). The average value and the upper value of the confidence interval for the HOMA-IR index were used, as well as the average value and the lower value of the confidence interval for the HOMA-%B. Area 1 reflects increased HOMA-IR and HOMA-%B. Area 2 reflects increased HOMA-IR and decreased HOMA-%B. The fasting insulinemia and glycemia values represent the means of 10 mice for each nutritional intervention.

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