Figure 6 | Scientific Reports

Figure 6

From: Extra virgin olive oil improved body weight and insulin sensitivity in high fat diet-induced obese LDLr−/−.Leiden mice without attenuation of steatohepatitis

Figure 6

Hierarchical clustering, Venn diagram and scatter plots of differential expression profiles of LFD, HFD-L, HFD-EVOO and HFD-OL liver genes. (A) Hierarchical clustering of differential expression profiles of LFD, HFD-L, HFD-EVOO and HFD-OL genes, performed using Euclidean distance according to expression pattern with the MeV software. Scaled expression value, expressed as the row Z-score, is plotted in yellow-blue color scale, with yellow indicating high expression and blue indicating low expression. (B) Venn diagram showing the number and percentage of DEGs (up-regulated and down-regulated) shared by HFD-L, HFD-EVOO and/or HFD-OL relative to LFD. (C) Scatter plot showing the fold change and statistical significance of genes when comparing HFD-L, HFD-EVOO or HFD-OL relative to LFD. The yellow and blue dots represent up- and down-regulated genes, respectively, with statistical significance. The grey dots represent the genes without significant differential expression.

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