Figure 5
From: ALKBH4 promotes tumourigenesis with a poor prognosis in non-small-cell lung cancer
The expression of ALKBH4 and E2F1of E2F1-target genes has a positive correlation in NSCLC clinical specimens. E2F1 (A) and E2F1-target gene ((B) CCNE1, (C) MYBL2, and (D) CDC25A) expression levels were measured using qPCR and were compared between normal and tumour tissues in NSCLC clinical specimens. Relative expression normalised to ACTB is shown. Data are represented as means ± S.D. ****p < 0.0001 for paired t-test. Correlation analysis was performed with the relative ALKBH4 expression and the relative E2F1 expression (E), CCNE1 expression (F), MYBL2 expression (G), and CDC25A expression (H) using 42-matched pairs of NSCLC samples. Pearson correlation analysis was conducted.
