Table 6 “KEGG 2019 Human” category of Enrichr for 53 genes (based on gene expression) and 200 genes (based on m6A) selected by applying KTD-based unsupervised FE to integration of gene expression and m6A profile. Fifteen terms with adjusted P-values less than 0.05 are listed.

Gene expression

Ribosome

20/153

\(2.13\times 10^{-29}\)

\(6.55\times 10^{-27}\)

Thermogenesis

13/231

\(2.59\times 10^{-14}\)

\(3.99\times 10^{-12}\)

Oxidative phosphorylation

11/133

\(4.44\times 10^{-14}\)

\(4.56\times 10^{-12}\)

Parkinson disease

11/142

\(9.22\times 10^{-14}\)

\(7.10\times 10^{-12}\)

Glycolysis/gluconeogenesis

8/68

\(9.16\times 10^{-12}\)

\(5.64\times 10^{-10}\)

HIF-1 signaling pathway

6/100

\(2.55\times 10^{-7}\)

\(1.31\times 10^{-5}\)

Alzheimer disease

7/171

\(3.27\times 10^{-7}\)

\(1.44\times 10^{-5}\)

Huntington disease

6/193

\(1.18\times 10^{-5}\)

\(4.53\times 10^{-4}\)

Retrograde endocannabinoid signaling

5/148

\(4.47\times 10^{-5}\)

\(1.53\times 10^{-3}\)

Cardiac muscle contraction

4/78

\(5.42\times 10^{-5}\)

\(1.67\times 10^{-3}\)

Non-alcoholic fatty liver disease (NAFLD)

4/149

\(6.52\times 10^{-4}\)

\(1.83\times 10^{-2}\)

m6A

Glycolysis/gluconeogenesis

7/68

\(5.21\times 10^{-6}\)

\(1.60\times 10^{-3}\)

Central carbon metabolism in cancer

6/65

\(4.69\times 10^{-5}\)

\(7.22\times 10^{-3}\)

HIF-1 signaling pathway

6/100

\(5.07\times 10^{-4}\)

\(5.21\times 10^{-2}\)

Glucagon signaling pathway

6/103

\(5.93\times 10^{-4}\)

\(4.57\times 10^{-2}\)