Table 2 Comparison of baseline parameters of study participants with IOP ≥ 30 mmHg (Group A), 21 mmHg ≤ IOP < 30 mmHg (Group B), and normal IOP (Group C).

From: The influence of different intraocular pressure on lamina cribrosa parameters in glaucoma and the relation clinical implication

 

Group A

Group B

Group C

P ValueA-B

P ValueA-C

P ValueB-C

No. of eyes

30

33

28

   

Age (years)

45.2 ± 18.2

41.1 ± 13.1

48.1 ± 14.9

0.300

0.509

0.504

Male sex (%)

66.7

72.7

53.6

0.608

0.317

0.125

OD (%)

53.3

42.4

46.4

0.395

0.607

0.759

BCVA

0.2 ± 0.2

0.5 ± 0.4

0.6 ± 0.3

0.004

< 0.001

0.190

Axial length (mm)

24.5 ± 2.1

23.9 ± 3.1

24.7 ± 2.6

0.359

0.792

0.300

VF MD (dB)

− 21.3 ± 7.6

− 15.6 ± 7.8

− 5.4 ± 5.5

0.008

< 0.001

< 0.001

CCT (μm)

502.3 ± 38.4

500.7 ± 33.9

496.8 ± 26.0

0.865

0.541

0.630

Instant IOP (mmHg)

29.2 ± 11.1

20.7 ± 9.7

17.4 ± 5.7

0.002

< 0.001

0.121

Maximum IOP (mmHg)

44.0 ± 8.4

29.3 ± 8.0

20.8 ± 5.4

< 0.001

< 0.001

< 0.001

Mean CDR

0.8 ± 0.1

0.7 ± 0.2

0.6 ± 0.2

0.446

< 0.001

0.013

Mean scan surface CDR

0.8 ± 0.1

0.7 ± 0.2

0.6 ± 0.2

0.257

< 0.001

0.004

CV (mm3)

0.8 ± 0.3

0.6 ± 0.4

0.4 ± 0.3

0.008

< 0.001

0.066

Mean RNFL thickness (mm)

42.8 ± 12.7

69.2 ± 19.9

80.6 ± 29.2

< 0.001

< 0.001

0.075

BMO (μm)

1722.3 ± 213.8

1736.5 ± 408.9

1733.3 ± 203.1

0.865

0.841

0.970

Cup depth (μm)

547.8 ± 202.6

342.8 ± 221.5

161.6 ± 166.0

< 0.001

< 0.001

< 0.001

LCD (μm)

655.3 ± 173.9

513.9 ± 154.8

404.5 ± 102.9

0.001

< 0.001

0.002

PLCSD (μm)

876.8 ± 160.4

739.7 ± 152.1

648.2 ± 124.4

< 0.001

< 0.001

0.014

PTT (μm)

107.5 ± 42.6

171.1 ± 131.2

242.9 ± 142.3

0.014

< 0.001

0.045

LCT (μm)

221.4 ± 69.8

225.8 ± 46.6

243.7 ± 47.3

0.770

0.163

0.142

LCCI (μm)

76.2 ± 28.0

58.0 ± 33.8

35.8 ± 29.2

0.024

 < 0.001

0.009

aLCCI (μm)

6.7 ± 2.4

4.5 ± 2.0

3.4 ± 2.4

< 0.001

< 0.001

0.043

BMO-MRW

129.6 ± 38.0

154.6 ± 67.3

195.1 ± 99.6

0.078

0.001

0.064

  1. aLCCI = adjusted lamina cribrosa curvature index; BCVA = best-corrected visual acuity; BMO = Bruch’s membrane opening; BMO-MRW = Bruch’s membrane opening minimum rim width; CCT = central corneal thickness; CDR = cup-disk ratio; CV = cup volume; IOP = intraocular pressure; LCCI = lamina cribrosa curvature index; LCD = lamina cribrosa depth; LCT = lamina cribrosa thickness; MD = mean deviation; PLCSD = posterior lamina cribrosa surface depth; PTT = prelaminar tissue thickness; RNFL = retinal nerve fiber layer; VF = visual field.
  2. All values < 0.05 at t-test are presented in boldface.
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