Table 2 CC50 (µM), EC50 (µM) and SI values for NSC47715, NSC85561 and NSC7223.
From: Potent sialic acid inhibitors that target influenza A virus hemagglutinin
Compounds | CC50 | EC50 | SI | Scorea | Energyb | VDWb | HBondb | Elecb | 2-D structure |
|---|---|---|---|---|---|---|---|---|---|
NSC47715 | > 1000 | 0.29 ± 0.02 | > 3448 | 3.233 | –126.11 | –72.98 | –49.83 | –3.30 |
|
NSC85561 | 700 | 2.42 ± 0.11 | 289 | 3.228 | –123.49 | –69.96 | –50.27 | –3.25 |
|
NSC7223 | 900 | 2.50 ± 0.76 | 360 | 3.227 | –127.09 | –71.48 | –53.31 | –2.30 |
|
