Figure 2

The cell surviving fraction estimated by the model. (A) The dose–response curve for 4-MU concentration of HT1080 cells. Blue solid line represents the survival fraction estimated by the log-logistic model (Eq. (1)), blue circle represents the experimental surviving fraction⁹. (B) The surviving fraction as a function of absorbed dose. R² value was calculated using Eq. (7). Charcoal line, red line and blue line represent the model prediction for the 0, 80 and 100 μM 4-MU cases, respectively. (C) The cell survival curve as a function of 4-MU concentration with a constant 4 Gy irradiation. Red line represents the IMK model prediction and red circles denote experimental data.