Table 1 Demographic characteristics and factors associated with HBV infection in mothers in the birth phase, Nha Trang, Vietnam, 2009–2010 (N = 1989).

From: Hepatitis B virus infection among pregnant mothers and children after the introduction of the universal vaccination program in Central Vietnam

Factors

Total N (%)

HBV infection in mothers n (% n/N)

OR (95% CI)

aOR (95% CI)

N = 1989

n = 250 (12.6%)

【Mothers】

HBsAg

Negative

1737 (87.4)

-

-

-

Positive

250 (12.6)

-

-

-

Anti-HBs antibody (mIU/ml)

 < 10

1033 (53.5)

226 (21.9)

Ref

Ref

 ≥ 10

898 (46.5)

18 (2.0)

0.1 (0.04, 0.1)

0.1 (0.04, 0.1)

Age (years old)

17–24

572 (28.8)

61 (10.7)

Ref

Ref

25–34

1164 (58.6)

158 (13.6)

1.3 (0.96, 1.8)

1.5 (1.1, 2.1)

35–44

250 (12.6)

31 (12.4)

1.2 (0.7, 1.9)

1.5 (0.9, 2.6)

Maternal Education

High school or higher

1060 (53.5)

110 (10.4)

Ref

Ref

None-Junior high school

920 (46.5)

139 (15.1)

1.5 (1.2–2.0)

1.5 (1.1, 2.0)

Residential Area

Urban

1395 (70.2)

176 (12.6)

Ref

-

Suburban

592 (29.8)

74 (12.5)

1.0 (0.7, 1.3)

-

Para

Multi

992 (49.9)

125 (12.6)

Ref

-

Primi

995 (50.1)

125 (12.6)

1.0 (0.8, 1.3)

-

Antenatal care

 ≥ 4times

1682 (84.7)

201 (12.0)

Ref

Ref

 < 4 times

305 (15.4)

49 (16.1)

1.4 (1.0, 2.0)

1.4 (0.96, 2.1)

BMI in prepregnancy

Normal-High

1475 (74.2)

183 (12.4)

Ref

-

Low

512 (25.8)

67 (13.1)

1.1 (0.8, 1.4)

-

Anemia

Negative

1478 (74.4)

191 (12.9)

Ref

-

Positive

509 (25.6)

59 (11.6)

0.9 (0.6, 1.2)

-

Mode of delivery

Vaginal

1156 (58.2)

137 (11.9)

Ref

-

Caesarian Section

831 (41.8)

113 (13.6)

1.2 (0.9, 1.5)

-

Term of delivery

Term-Postterm

1919 (96.6)

244 (12.7)

Ref

-

Preterm

68 (3.4)

6 (8.8)

0.7 (0.3, 1.6)

-

  1. Logistic regression was used for projecting odds ratios (OR) in univariate analysis and adjusted odds ratios (aOR) in multivariate analysis.
  2. Variables with statistical significance were underlined when 95%CI of aOR did not include 1.
  3. HBsAg: hepatitis B surface antigen; HBV: hepatitis B virus; N: number; OR: odds ratio; CI: confidence interval; aOR: adjusted odds ratio; anti-HBs antibody: anti-hepatitis B surface antibody; HBeAg: hepatitis B e antigen; BMI: body mass index; and Ref.: reference.