Table 4 Demographic characteristics and factors associated with anti-HBs antibody below the seroprotective level in children in the 2-year follow-up phase, Nha Trang, Vietnam, 2011–2012 (N = 1338).
Factors | Total N (%) | Anti-HBs antibody below the seroprotective level n (% n/N) | OR (95%CI) | aOR (95%CI) |
|---|---|---|---|---|
N = 1338 | n = 203 (15.2%) | |||
[Children] | ||||
HBsAg | ||||
Negative | 1313 (98.1) | 191 (14.6) | Ref | Ref |
Positive | 26 (1.9) | 12 (46.2) | 5.0 (2.3, 11.0) | 5.5 (2.4, 12.2) |
Sex | ||||
Female | 639 (47.7) | 81 (12.7) | Ref | Ref |
Male | 700 (52.3) | 122 (17.5) | 1.5 (1.1, 2.0) | 1.5(1.1, 2.0) |
Immunization status of HepB | ||||
No or Incomplete | 315 (23.5) | 62 (19.7) | Ref | Ref |
Complete | 1024 (76.5) | 141 (13.8) | 0.7 (0.5–0.9) | 0.7 (0.5–0.9) |
Timing of HepB-BD | ||||
No | 229 (17.1) | 39 (17.0) | Ref | - |
Day 0–1 | 1104 (82.5) | 163 (14.8) | 0.8 (0.6, 1.2) | - |
Day 2–7 | 6 (0.5) | 1 (16.7) | 1.0 (0.1, 8.6) | - |
HBIG at birth | ||||
No | 1333 (99.8) | 202 (15.2) | Ref | - |
Yes | 3 (0.2) | 0 (0) | * | - |
[Mothers] | ||||
HBsAg | ||||
Negative | 1173 (87.6) | 170 (14.5) | Ref | - |
Positive | 166 (12.4) | 33 (19.9) | 1.5 (0.97, 2.2) | - |
Age (years old) | ||||
17–24 | 385 (28.9) | 50 (13.0) | Ref | Ref |
25–34 | 769 (57.8) | 115 (15.0) | 1.2 (0.8, 1.7) | 1.2 (0.9, 1.8) |
35–44 | 177 (13.3) | 37 (21.0) | 1.8 (1.1, 2.9) | 1.9 (1.2, 3.1) |
BMI in prepregnancy | ||||
Normal-High | 997 (74.5) | 150 (15.1) | Ref | - |
Low | 342 (25.5) | 53 (15.5) | 1.0 (0.7, 1.5) | - |
Mode of delivery | ||||
Vaginal | 766 (57.2) | 124 (16.2) | Ref | - |
Caesarian Section | 573 (42.8) | 79 (13.8) | 0.8 (0.6, 1.1) | - |
