Figure 3 | Scientific Reports

Figure 3

From: Differences in host immune populations between rhesus macaques and cynomolgus macaque subspecies in relation to susceptibility to Mycobacterium tuberculosis infection

Figure 3

Principle component analysis of immune parameters between macaque groups using the immunophenotyping data and correlations with pathology scores. (A) PCA loading plot of immune parameters, with a scale for relative contribution of each component to the model. Red = highest to grey = lowest, (B) PCA biplot showing how the macaque populations cluster towards the variables that contribute the most to the variation in the data. Largest of each shape indicates the mean of each population with smaller shapes indicating the outliers. Blue circles = CCM, yellow triangles = ICM, grey squares = MCM, red crosses = RM (C) Correlation of CD4 + T-cells with pathology scores following TB infection, with each population indicated by a different colour, red = CCM, green = ICM, blue = MCM and red = RM (D) Correlation of CD8 + T-cells with pathology scores following TB infection, with each population indicated by a different colour, red = CCM, green = ICM, blue = MCM and red = RM.

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