Figure 1
From: Extracellular vesicles from dHL-60 cells as delivery vehicles for diverse therapeutics

The naïve HL-60 cells and dHL-60 cells release a heterogeneous population of EVs. (a) Representative images showing EVs released from HL-60 cells and dHL-60 cells stimulated with fMLP. The arrow indicates membrane protrusions during EVs release. (b) Quantification of relative amounts of EVs derived from the naïve HL-60 and dHL-60 cells pre-stained with calcein-AM in the presence or absence of fMLP stimulation. (c) A representative plot showing the size and concentration of EVs derived from the HL-60 cells, dHL-60 cells, and neutrophils stimulated with fMLP. (d) Scanning electron microscopic analysis of EVs generated from HL-60 and dHL-60 cells. The data shown are the mean ± SEM. *P < 0.05; **P < 0.01.