Figure 4
From: Extracellular vesicles from dHL-60 cells as delivery vehicles for diverse therapeutics
The delivery of miRNA-16 using dHL-60 cell-derived EVs. (a) Left panels, fluorescence levels of the miRNA-16 precursor in the HL-60 and dHL-60 cells. Right panels, fluorescence levels of the miRNA-16 precursor in EVs derived from the HL-60 and dHL-60 cells. (b) Left panels, fluorescence levels of the miRNA-16 mimic in the HL-60 and dHL-60 cells. Right panels, fluorescence levels of the miRNA-16 mimic in EVs derived from the HL-60 and dHL-60 cells. (c) The effects of EVs on the proliferation of the MCF-7, Jurkat, and dTHP-1 cells. (d) The effects of EVs on expressions of iNOS and arginase in MCF-7, Jurkat, and dTHP-1 cells. (e) The expression of iNOS in the dTHP-1 cells exposed to the HL-60 and dHL-60 cells. All data represent three independent experiments; mean ± SEM. *P < 0.05; **P < 0.01; ***P < 0.001.
