Table 4 Clinical outcomes according to age.
Univariable analysis | Angina | AMI | ||||||
---|---|---|---|---|---|---|---|---|
Age < 65 years (n = 22,956) | Age ≥ 65 years (n = 27,300) | Age < 65 years (n = 21,233) | Age ≥ 65 years (n = 18,816) | |||||
Depression with Non-depression | Depression with Non-depression | Depression with Non-depression | Depression with Non-depression | |||||
In-hospital outcome | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value |
In-hospital mortality | 2.769 (1.505–5.094) | 0.001 | 0.966 (0.712–1.311) | 0.824 | 1.265 (0.774–2.067) | 0.349 | 1.277 (1.069–1.525) | 0.007 |
Follow-up outcome | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value |
All-cause Death | 2.614 (2.066–3.308) | < 0.001 | 1.184 (1.067–1.315) | 0.002 | 1.935 (1.455–2.574) | < 0.001 | 1.310 (1.174–1.461) | < 0.001 |
Propensity score matching analysis | Angina | AMI | ||||||
---|---|---|---|---|---|---|---|---|
Age < 65 years (n = 2,368) | Age ≥ 65 years (n = 6,152) | Age < 65 years (n = 1,288) | Age ≥ 65 years (n = 3,394) | |||||
Depression with Non-depression | Depression with Non-depression | Depression with Non-depression | Depression with Non-depression | |||||
Clinical outcomes | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value |
In-hospital mortality | 2.010 (0.752–5.374) | 0.164 | 0.822 (0.557–1.213) | 0.323 | 1.719 (0.781–3.783) | 0.178 | 1.131 (0.887–1.443) | 0.322 |
Follow-up outcome | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value |
All-cause Death | 1.769 (1.240–2.525) | 0.002 | 1.062 (0.925–1.221) | 0.394 | 1.272 (0.848–1.906) | 0.245 | 1.079 (0.933–1.248) | 0.307 |
Propensity score matching analysis for AD medicated depression | Angina | AMI | ||||||
---|---|---|---|---|---|---|---|---|
Age < 65 years (n = 2,006) | Age ≥ 65 years (n = 5,042) | Age < 65 years (n = 1,050) | Age ≥ 65 years (n = 2672) | |||||
Depression with Non-depression | Depression with Non-depression | Depression with Non-depression | Depression with Non-depression | |||||
Clinical outcomes | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value | Odds ratio (95% CI) | P-value |
In-hospital mortality | 5.040 (1.102–23.063) | 0.037 | 1.149 (0.723–1.867) | 0.556 | 1.158 (0.546–2.458) | 0.702 | 1.098 (0.840–1.437) | 0.494 |
Follow-up outcome | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value | Hazard ratio (95% CI) | P-value |
All-cause Death | 1.592 (1.083–2.341) | 0.018 | 1.111 (0.953–1.295) | 0.178 | 1.412 (0.891–2.237) | 0.142 | 1.178 (0.998–1.390) | 0.053 |