Table 2 Vital signs, clinical symptoms, and morbidities in patients with different disease severities.

From: Clinical features and disease severity in an Iranian population of inpatients with COVID-19

Feature

Disease severity

P1

P2***

Mild/moderate (N = 33)

Severe (N = 139)

Critical (N = 28)

Vital signs

Pulse rate

87.12 ± 20.12

94.71 ± 26.64

106.48 ± 26.36

0.003**

 < 0.001

Respiratory rate

20.12 ± 1.97

26.64 ± 6.87

26.36 ± 6.76

 < 0.001**

 < 0.001

BP (mmHg)

126.71 ± 21.98

126.74 ± 15.42

129.68 ± 23.68

0.478**

0.467

Temperature (°C)

37.63 ± 0.65

37.65 ± 0.66

37.98 ± 0.83

0.742**

0.084

O2 saturation (%)

95.48 ± 1.25

87.80 ± 6.37

82.15 ± 10.00

 < 0.001**

 < 0.001

Symptoms

Fever

23 (69.7)

101 (72.7)

19 (67.9)

0.802*

0.849

Dyspnea

24 (72.7)

123 (88.5)

24 (85.7)

0.023*

0.069

Nausea/vomiting

11 (33.3)

22 (15.8)

4 (14.3)

0.016*

0.055

Cough

29 (87.9)

129 (92.8)

25 (89.3)

0.414*

0.595

Diarrhea

8 (24.2)

19 (13.7)

2 (7.1)

0.082*

0.148

Conjunctivitis

0 (0.0)

2 (1.4)

0 (0.0)

0.528*

0.642

Myalgia

16 (48.5)

69 (49.6)

15 (53.6)

0.849*

0.914

Arthralgia

7 (21.2)

18 (12.9)

2 (7.1)

0.156*

0.261

Weakness

16 (48.5)

65 (46.8)

14 (50.0)

0.901*

0.945

Abdominal pain

1 (3.0)

6 (4.3)

0 (0.0)

0.872*

0.519

Seizure

0 (0.0)

1 (0.7)

0 (0.0)

0.656*

0.802

Headache

3 (9.1)

26 (18.7)

2 (7.1)

0.266*

0.164

Sore throat

1 (3.0)

19 (13.7)

2 (7.1)

0.109*

0.167

Chill

10 (30.3)

28 (20.1)

7 (25.0)

0.240*

0.428

Hyposmia

4 (12.1)

11 (7.9)

2 (7.1)

0.414*

0.710

Fatigue

9 (27.3)

40 (28.8)

7 (25.0)

0.919*

0.916

Confusion

0 (0.0)

2 (1.4)

3 (10.7)

0.517*

0.043

Rhinorrhea

1 (3.0)

3 (2.2)

0 (0.0)

0.802*

0.681

Morbidities

Shock

0 (0.0)

1 (0.7)

6 (21.4)

0.231*

 < 0.001

Sepsis

0 (0.0)

1 (0.7)

8 (28.6)

0.172*

 < 0.001

ARDS

0 (0.0)

1 (0.7)

27 (96.4)

0.011*

 < 0.001

DHF

0 (0.0)

1 (0.7)

0 (0.0)

 > 0.999*

0.802

ATN

0 (0.0)

1 (0.7)

1 (3.6)

 > 0.999*

0.288

Coagulopathy

0 (0.0)

0 (0.0)

1 (3.6)

 > 0.999*

0.046

Acidosis

0 (0.0)

0 (0.0)

1 (3.6)

 > 0.999*

0.046

ICU admission

0 (0.0)

0 (0.0)

14 (50.0)

0.085*

 < 0.001

Intubation

0 (0.0)

0 (0.0)

23 (82.1)

0.023*

 < 0.001

  1. BP blood pressure, ARDS acute respiratory distress syndrome, DHF diastolic heart failure, ATN acute tubular necrosis, ICU intensive care unit.
  2. P1: Comparison between mild/moderate and severe/critical groups.
  3. P2: Comparison between mild/moderate, severe, and critical groups.
  4. Bold values are statistically significant (P < 0.05).
  5. *Chi-square or Fisher’s exact test.
  6. **Mann–Whitney test.
  7. ***Kruskal–Wallis test.
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