Scientific Reports

Table 1 Subject characteristics.

From: Induced pluripotent stem cells from subjects with Lesch-Nyhan disease

	LND Cases			Healthy controls
	A	D	T	A	B	C
Sex	Male	Male	Male	Male	Male	Male
Age^a	15	10	46	21	43	22
Race	Black	Caucasian	Caucasian	Caucasian	Black	Caucasian
HPRT1 gene variant	c.151C > T	c.508C > T	c.371insTT	none	none	none
HGprt consequence	Premature stop	Premature stop	Frame shift, premature stop	Normal	Normal	Normal
Clinical features^b	Classic	Classic	Classic	Normal	Normal	Normal
iPSC lines	L3.29 L3.30	L2.09 L2.12	L1.02 L1.04	C1.02 C1.03	C2.04 C2.06	C3.05 C3.08

^aAge relates to subject age at skin biopsy.
^bClinical features of classic LND include motor dysfunction resembling cerebral palsy, cognitive impairment, self-injurious behavior, and overproduction of uric acid.

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