Table 3 Multivariate models for miR-126 in (A) tumor and (B) stroma (cox proportional hazards test, n = 452).
From: High expression of microRNA-126 relates to favorable prognosis for colon cancer patients
(A) | 95.0% CI | (B) | 95.0% CI | |||||
|---|---|---|---|---|---|---|---|---|
p | HR | Lower | Upper | p | HR | Lower | Upper | |
Age at diagnosis | 0.002 | 1.03 | 1.01 | 1.05 | 0.003 | 1.03 | 1.01 | 1.05 |
Differentiation | 0.032 | 0.027 | ||||||
Well differentiated | 1.00 | 1.00 | ||||||
Moderately differentiated | 0.500 | 0.76 | 0.35 | 1.68 | 0.706 | 0.86 | 0.39 | 1.89 |
Poorly differentiated | 0.322 | 0.63 | 0.26 | 1.57 | 0.653 | 0.81 | 0.33 | 2.01 |
Undifferentiated | 0.052 | 4.02 | 0.99 | 16.36 | 0.020 | 5.27 | 1.30 | 21.46 |
pTNM | < 0.001 | < 0.001 | ||||||
pTNM-stage I | 1.00 | 1.00 | ||||||
pTNM-stage II | 0.123 | 2.12 | 0.82 | 5.53 | 0.122 | 2.12 | 0.82 | 5.51 |
pTNM-stage III | < 0.001 | 7.35 | 2.89 | 18.72 | < 0.001 | 6.76 | 2.66 | 17.18 |
miR-126 tumor | ||||||||
Low | 1.00 | |||||||
High | 0.002 | 0.46 | 0.27 | 0.76 | ||||
miR-126 stroma | ||||||||
Low | 1.00 | |||||||
High | 0.049 | 0.55 | 0.30 | 1.00 | ||||
