Figure 7 | Scientific Reports

Figure 7

From: Vegfa promoter gene hypermethylation at HIF1α binding site is an early contributor to CKD progression after renal ischemia

Figure 7

Global DNA methylation over the course of AKI to CKD transition. (A) Percentage change of global DNA methylation in renal cortex from the UNx (gray squares) and IR + UNx (black triangles) groups. (B) Percentage change of global DNA methylation in renal medulla from the UNx (gray squares) and IR + UNx (black triangles) groups, for each studied period: 30, 60, 90, and 120 days The one-way analysis of variance (ANOVA) was used to determine statistical differences, using the Bonferroni correction for multiple comparisons. *p < 0.05 versus S group.

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