Table 1 Urine Chemistries along the study for all the included groups.

From: Vegfa promoter gene hypermethylation at HIF1α binding site is an early contributor to CKD progression after renal ischemia

 

Urinary flow (mL/min)

FENa (%)

Osmolarity (mOsm/L)

Sham

30 days

0.031 ± 0.004

0.17 ± 0.03

350 ± 77

60 days

0.026 ± 0.007

0.10 ± 0.00

481 ± 107

90 days

0.023 ± 0.003

0.11 ± 0.02

729 ± 123

120 days

0.014 ± 0.003

0.08 ± 0.03

1226 ± 178

UNx

30 days

0.029 ± 0.005

0.19 ± 0.04

494 ± 172

60 days

0.025 ± 0.005

0.15 ± 0.05

703 ± 119

90 days

0.014 ± 0.007

0.16 ± 0.04

936 ± 72

120 days

0.024 ± 0.004

0.09 ± 0.02

746 ± 129

IR + UNx

30 days

0.026 ± 0.005

0.21 ± 0.07

448 ± 59

60 days

0.037 ± 0.003

0.26 ± 0.14

440 ± 39

90 days

0.030 ± 0.002

0.24 ± 0.07

501 ± 30

120 days

0.024 ± 0.004

0.20 ± 0.08

678 ± 145*

  1. *p < 0.05 versus respective Sham.