Table 3 Characteristics of female subjects divided by tertiles of FLI at baseline (n = 5086).

From: Fatty liver index is independently associated with deterioration of renal function during a 10-year period in healthy subjects

 

T1 [0.4–4.2]

T2 [4.3–12.0]

T3 [12.1–99.3]

P

n = 1702

n = 1681

n = 1703

Age (years)

41 ± 9

47 ± 10

51 ± 10

< 0.001

Body mass index

19 ± 2

21 ± 2

25 ± 3

< 0.001

Waist circumference (cm)

71 ± 5

78 ± 5

87 ± 8

< 0.001

Systolic blood pressure (mmHg)

104 ± 13

109 ± 15

117 ± 16

< 0.001

Diastolic blood pressure (mmHg)

65 ± 9

69 ± 10

74 ± 10

< 0.001

Smoking habit

294 (18.2)

288 (17.9)

337 (20.5)

0.123

Alcohol drinking habit

374 (22.0)

462 (27.5)

465 (27.3)

< 0.001

Comorbidity

Hypertension

48 (2.8)

125 (7.4)

341 (20.0)

< 0.001

Diabetes mellitus

6 (0.4)

19 (1.1)

73 (4.3)

< 0.001

Dyslipidemia

334 (19.6)

385 (22.9)

504 (29.6)

< 0.001

Biochemical data

Hemoglobin (g/dL)

12.7 ± 1.2

12.8 ± 1.2

13.2 ± 1.1

< 0.001

Platelet (104/μL)

23.7 ± 5.0

24.6 ± 5.4

25.7 ± 5.7

< 0.001

Albumin (g/dL)

4.3 ± 0.2

4.3 ± 0.2

4.3 ± 0.2

0.065

Blood urea nitrogen (mg/dL)

12.9 ± 3.2

13.1 ± 3.1

13.4 ± 3.3

< 0.001

Creatinine (mg/dL)

0.59 ± 0.08

0.59 ± 0.08

0.58 ± 0.08

0.131

eGFR (mL/min/1.73 m2)

90.8 ± 14.7

87.3 ± 14.7

86.4 ± 14.6

< 0.001

Uric acid (mg/dL)

4.0 ± 0.8

4.3 ± 0.9

4.8 ± 1.0

< 0.001

AST (U/L)

18 (16–20)

18 (16–21)

20 (17–24)

< 0.001

ALT (U/L)

13 (11–16)

14 (12–18)

19 (15–27)

< 0.001

γ-GTP (U/L)

14 (12–18)

17 (14–23)

27 (19–42)

< 0.001

FPG (mg/dL)

84 ± 9

86 ± 12

92 ± 16

< 0.001

Hemoglobin A1c (%)

5.1 ± 0.4

5.2 ± 0.4

5.4 ± 0.6

< 0.001

LDL cholesterol (mg/dL)

105 ± 26

117 ± 29

130 ± 31

< 0.001

HDL cholesterol (mg/dL)

74 ± 14

71 ± 14

63 ± 15

< 0.001

Triglycerides (mg/dL)

48 (39–59)

67 (53–82)

98 (75–133)

< 0.001

  1. Variables are expressed as number (%), means ± SD or medians (interquartile ranges).
  2. AST aspartate aminotransferase, ALT alanine aminotransferase, eGFR estimated glomerular filtration rate, FLI fatty liver index, FPG fasting plasma glucose, γ-GTP γ-glutamyl transferase, HDL high-density lipoprotein, LDL low-density lipoprotein.