Table 2 Association between survival and IASLC/ATS/ERS classification of dominant tumor (DT).

From: Prognostic histologic subtyping of dominant tumor in resected synchronous multiple adenocarcinomas of lung

Variables

Grade (N = 149); %

Low (N = 32); %

Intermediate (N = 87); %

High (N = 30); %

p value

5-year overall survival (%)

88.6

96.9

94.3

63.3

< 0.001

5-year disease-free survival (%)

78.5

100

87.2

30.0

< 0.001

Follow-up period (months)

80.4 ± 34.8

66.3 ± 23.2

89.5 ± 36.8

69.0 ± 31.6

0.001

Disease-free duration (months)

69.4 ± 37.1

66.3 ± 23.2

80.9 ± 37.9

39.6 ± 29.5

< 0.001*

Total recurrence, no.

44 (29.5)

0

20 (23.3)

24 (80.0)

< 0.001

Patterns of recurrence

    

0. 595**

Local only

13 (29.5)

0

7 (35.0)

6 (25.0)

 

Distant only

12 (27.3)

0

6 (30.0)

6 (25.0)

 

Local + Distant

19 (43.2)

0

7 (35.0)

12 (50.0)

 
  1. *ANOVA Test.
  2. **Chi-Square tests, compared between intermittent and high grade groups.