Table 1 Maternal background and obstetric outcomes based on serum IgE levels.

From: Immunoglobulin E levels and pregnancy-induced hypertension: Japan Environment and Children’s Study

Variable

Participants

p-value

Total IgE < 170 IU/ml

Total IgE ≥ 170 IU/ml

n = 24,878

n = 7640

Maternal medical background

Gestational age at the time of blood sample collection, mean weeks (SD)

15.6 (3.2)

15.6 (3.3)

0.068a

Maternal age, mean years (SD)

30.1 (5.1)

29.3 (5.2)

 < 0.01a

Maternal age category, %

19

1.3

2.4

 < 0.01b

20–29

46.1

51.3

30–39

48.7

43.7

 ≥ 40

4.0

2.6

Timing at measure maternal blood pressure, weeks mean (SD)

11.1 (1.8)

11.1 (1.8)

0.300a

Systolic blood pressure in the first trimester, mean mmHg (SD)

111 (15)

111 (12)

0.232a

Diastolic blood pressure in the first trimester, mean mmHg (SD)

64 (13)

64 (14)

0.098a

BMI before pregnancy (kg/m2), %

 < 18.5

17.7

16.9

 < 0.01b

18.5–25.0

74.0

73.4

 > 25.0

8.3

9.7

Smoking during pregnancy, %

3.2

4.8

 < 0.01b

SLE, %

0.1

0.1

0.698b

Maternal education, year, %

 < 10

3.3

4.7

 < 0.01b

10–12

28.8

30.3

13–16

43.0

41.1

 ≥ 17

24.9

23.9

Obstetric outcomes

Gestational age at delivery, weeks mean (SD) (%)

38.7 (2.2)

38.8 (2.1)

0.016a

PIH

3.2

3.6

0.114b

Eo-PIH

0.6

0.5

0.351b

Lo-PIH

2.3

2.7

0.058b

  1. IgE immunoglobulin E, SD standard deviation, BMI body mass index, SLE systemic lupus erythematosus, PIH pregnancy induced hypertension, Eo early-onset, Lo late-onset.
  2. ap-value, t-test.
  3. bp-value, chi-square test.