Table 1 Maternal background and obstetric outcomes based on serum IgE levels.
From: Immunoglobulin E levels and pregnancy-induced hypertension: Japan Environment and Children’s Study
Variable | Participants | p-value | |
---|---|---|---|
Total IgE < 170 IU/ml | Total IgE ≥ 170 IU/ml | ||
n = 24,878 | n = 7640 | ||
Maternal medical background | |||
Gestational age at the time of blood sample collection, mean weeks (SD) | 15.6 (3.2) | 15.6 (3.3) | 0.068a |
Maternal age, mean years (SD) | 30.1 (5.1) | 29.3 (5.2) | < 0.01a |
Maternal age category, % | |||
≦19 | 1.3 | 2.4 | < 0.01b |
20–29 | 46.1 | 51.3 | |
30–39 | 48.7 | 43.7 | |
≥ 40 | 4.0 | 2.6 | |
Timing at measure maternal blood pressure, weeks mean (SD) | 11.1 (1.8) | 11.1 (1.8) | 0.300a |
Systolic blood pressure in the first trimester, mean mmHg (SD) | 111 (15) | 111 (12) | 0.232a |
Diastolic blood pressure in the first trimester, mean mmHg (SD) | 64 (13) | 64 (14) | 0.098a |
BMI before pregnancy (kg/m2), % | |||
< 18.5 | 17.7 | 16.9 | < 0.01b |
18.5–25.0 | 74.0 | 73.4 | |
> 25.0 | 8.3 | 9.7 | |
Smoking during pregnancy, % | 3.2 | 4.8 | < 0.01b |
SLE, % | 0.1 | 0.1 | 0.698b |
Maternal education, year, % | |||
< 10 | 3.3 | 4.7 | < 0.01b |
10–12 | 28.8 | 30.3 | |
13–16 | 43.0 | 41.1 | |
≥ 17 | 24.9 | 23.9 | |
Obstetric outcomes | |||
Gestational age at delivery, weeks mean (SD) (%) | 38.7 (2.2) | 38.8 (2.1) | 0.016a |
PIH | 3.2 | 3.6 | 0.114b |
Eo-PIH | 0.6 | 0.5 | 0.351b |
Lo-PIH | 2.3 | 2.7 | 0.058b |