Table 3 Pathway definitions used in the pathway-level analysis.

From: Gene network and biological pathways associated with susceptibility to differentiated thyroid carcinoma

Database

Definitions (N)

Definition tagged with oncoarray SNPs (N)

Definitions with PEMPa < 0.05 (N)

Source

Version

KEGG (HSA and BRITE definitions)

380

361

21

https://www.genome.jp/kegg-bin/get_htext?hsa00001.keg

v88 (Oct, 2018)

REACTOME

2020

1698

75

https://reactome.org/download/current/ReactomePathways.txt

v66 (Sep 2018)

GO biological process

5214

5203

253

GO database: http://purl.obolibrary.org/obo/go/go-basic.obo

GO annotations: https://ftp.ncbi.nlm.nih.gov/gene/DATA/gene2go.gz

(Oct 2018)

GO cellular component

655

652

38

GO molecular function

1060

1059

31

  1. aEmpirical p-value of the association test with DTC risk at the pathway level.
Back to article page