Table 1 Baseline characteristics by median H-Ficolin concentration.
H-ficolin < 31.18 μg/ml | H-ficolin ≥ 31.18 μg/ml | P | P19 tests | |
|---|---|---|---|---|
n | 1205 | 1205 | ||
Sex (woman) | 711 (59.0%) | 432 (35.9%) | < 0.001 | < 0.001 |
Age (years) | 36.7 (11.3) | 37.5 (11.4) | 0.11 | 1 |
Diabetes duration (years) | 21.4 (12.1) | 21.7 (11.3) | 0.51 | 1 |
Diabetes onset age (years) | 15.3 (8.8) | 15.8 (9.1) | 0.23 | 1 |
BMI (kg/m2) | 24.7 (3.4) | 25.3 (3.7) | < 0.001 | < 0.001 |
Systolic blood pressure (mmHg) | 133 (19) | 136 (19) | < 0.001 | 0.004 |
Diastolic blood pressure (mmHg) | 79 (10) | 81 (11) | < 0.001 | < 0.001 |
Retinal laser treatment (yes) | 436 (36.4%) | 503 (42.1%) | 0.005 | 0.95 |
RAAS inhibitor (yes) | 316 (26.4%) | 440 (36.9%) | < 0.001 | < 0.001 |
Lipid-lowering medication (yes) | 91 (7.6%) | 149 (12.5%) | < 0.001 | 0.002 |
Smoking status | < 0.001 | < 0.001 | ||
Current | 225 (19.5%) | 322 (28.4%) | ||
Former | 257 (22.3%) | 266 (23.4%) | ||
Never | 673 (58.3%) | 547 (48.2%) | ||
HbA1c (mmol/mol) | 66.9 (15.9) | 71.2 (16.1) | < 0.001 | < 0.001 |
Total cholesterol (mmol/l) | 4.86 (0.91) | 5.19 (1.08) | < 0.001 | < 0.001 |
HDL-cholesterol (mmol/l) | 1.29 (0.35) | 1.18 (0.35) | < 0.001 | < 0.001 |
Triglycerides (mmol/l) | 0.99 [0.77, 1.42] | 1.23 [0.87, 1.81] | < 0.001 | < 0.001 |
LDL-cholesterol (mmol/l) | 3.03 (0.83) | 3.33 (0.93) | < 0.001 | < 0.001 |
DKD category at baseline | < 0.001 | < 0.001 | ||
Normal AER | 750 (62.2%) | 662 (54.9%) | ||
Microalbuminuria | 152 (12.6%) | 161 (13.4%) | ||
Macroalbuminuria | 182 (15.1%) | 272 (22.6%) | ||
ESRD | 121 (10.0%) | 110 (9.1%) | ||
eGFR (ml/min/1.73 m2) | 84 [67, 100] | 83 [61, 99] | 0.04 | 0.76 |
AER (mg/24 h) | 11 [6, 41] | 16 [7, 121] | < 0.001 | < 0.001 |
