Table 2 Significant associations between maternal and perinatal factors and risk of pediatric central nervous system tumors.

Maternal race/ethnicity

Non-hispanic white

874 (45.2)

7942 (41.0)

Reference

Reference

Non-hispanic black

194 (10.0)

2254 (11.7)

0.78

0.66–0.92

0.003

0.79

0.67–0.93

0.004

Hispanic

807 (41.7)

8473 (43.8)

0.87

0.78–0.96

0.005

0.88

0.78–0.98

0.019

Other

59 (3.1)

671 (3.5)

0.79

0.61–1.05

0.110

0.76

0.57–1.01

0.060

Missing

0

0

Infant sex

Male

1032 (53.4)

9821 (50.8)

Reference

Reference

Female

902 (46.6)

9519 (49.2)

0.90

0.82–0.99

0.031

0.89

0.81–0.99

0.024

Missing

0 (0.0)

0 (0.0)

Size for gestational age

< 10th percentile

253 (13.1)

2640 (13.7)

0.98

0.85–1.13

0.795

0.98

0.85–1.13

0.819

10th–90th percentile

1453 (75.1)

14,883 (76.9)

Reference

Reference

> 90th percentile

200 (10.3)

1616 (8.4)

1.27

1.08–1.48

0.003

1.26

1.07–1.47

0.004

Missing

28 (1.5)

201 (1.0)

Gestational age

< 37 weeks

252 (13.0)

2203 (11.4)

1.18

1.02–1.35

0.024

1.19

1.04–1.38

0.013

37–41 weeks

1599 (82.7)

16,431 (84.9)

Reference

Reference

≥ 42

55 (2.8)

514 (2.7)

1.09

0.83–1.46

0.511

1.12

0.84–1.48

0.444

Missing

28 (1.5)

192 (1.0)

Continuous

0.98

0.96–1.00

0.052

0.98

0.96–0.99

0.033

Delivery type

Vaginal spontaneous

1225 (63.3)

12,886 (66.6)

Reference

Reference

Vaginal forceps or vacuum

144 (7.4)

1110 (5.7)

1.36

1.14–1.64

0.001

1.35

1.12–1.62

0.002

Cesarean

564 (29.2)

5331 (27.6)

1.11

1.00–1.24

0.045

1.10

0.99–1.23

0.067

Missing

1 (0.1)

13 (0.1)

Birth weight (g)

< 2500

166 (8.6)

1,498 (7.8)

1.14

0.96–1.35

0.131

1.15

0.97–1.37

0.105

2500–3999

1596 (82.5)

16,396 (84.7)

Reference

Reference

≥ 4000

172 (8.9)

1433 (7.4)

1.23

1.04–1.46

0.014

1.18

0.99–1.40

0.051

Missing

0 (0.0)

13 (0.1)

Continuous

1.00

0.99–1.00

0.207

1.00

0.99–1.00

0.541