Table 4 Significant associations between maternal and perinatal factors and survival of pediatric central nervous system tumor cases.

From: Maternal and perinatal factors are associated with risk of pediatric central nervous system tumors and poorer survival after diagnosis

Maternal and perinatal characteristics

All nervous system tumors

Cases

Unadjusted model

Adjusted modela

HR

95% CI

P-valueb

HR

95% CI

P-valueb

Maternal race/ethnicity

Non-hispanic white

874 (45.2)

Reference

Reference

Non-hispanic black

194 (10.0)

1.51

1.11–2.05

0.009

1.53

1.12–2.09

0.008

Hispanic

807 (41.7)

1.41

1.15–1.73

0.001

1.45

1.16–1.80

0.001

Other

59 (3.1)

1.69

1.05–2.76

0.033

1.71

1.04–2.82

0.036

Missing

0 (0.0)

      

Delivery type

Vaginal spontaneous

1225 (63.3)

Reference

Reference

Vaginal forceps or vacuum

144 (7.4)

0.78

0.52–1.17

0.229

0.79

0.53–1.20

0.277

Cesarean

564 (29.2)

1.29

1.05–1.57

0.014

1.28

1.05–1.57

0.016

Missing

1 (0.1)

      
  1. aAdjusted for birth year, sex, maternal race/ethnicity, maternal education, and tumor malignancy.
  2. bBonferroni corrected reference P values: 0.003 for an experiment-wide significance of 0.05.
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