Table 5 Significant associations between maternal and perinatal factors and survival of pediatric astrocytoma, ependymoma, and medulloblastoma cases.
Maternal and perinatal characteristics | Astrocytoma | ||||||
---|---|---|---|---|---|---|---|
Cases | Unadjusted model | Adjusted modela | |||||
HR | 95% CI | P-valueb | HR | 95% CI | P-valueb | ||
Maternal race/ethnicity | |||||||
Non-hispanic white | 480 (49.5) | Reference | Reference | ||||
Non-hispanic black | 101 (10.4) | 1.68 | 1.11–2.56 | 0.015 | 1.66 | 1.08–2.56 | 0.020 |
Hispanic | 357 (36.8) | 1.27 | 0.94–1.72 | 0.121 | 1.30 | 0.95–1.79 | 0.105 |
Other | 32 (3.3) | 1.89 | 0.98–3.64 | 0.056 | 1.98 | 0.99–3.95 | 0.054 |
Missing | 0 (0.0) | ||||||
Ependymoma | |||||||
Maternal nativity | |||||||
U.S. born | 99 (63.1) | Reference | Reference | ||||
Mexico | 40 (25.5) | 1.16 | 0.59–2.29 | 0.667 | 1.19 | 0.54–2.69 | 0.659 |
Other | 17 (10.8) | 2.11 | 0.96–4.66 | 0.065 | 2.50 | 1.05–5.98 | 0.039 |
Missing | 1 (0.6) | ||||||
Medulloblastoma | |||||||
Size for gestational age | |||||||
< 10th percentile | 27 (12.4) | 2.09 | 1.10–3.96 | 0.024 | 3.12 | 1.56–6.24 | 0.001 |
10th–90th percentile | 164 (75.6) | Reference | Reference | ||||
> 90th percentile | 24 (11.1) | 1.11 | 0.52–2.38 | 0.782 | 1.01 | 0.46–2.21 | 0.984 |
Missing | 2 (0.9) |