Figure 1 | Scientific Reports

Figure 1

From: Vortioxetine ameliorates anhedonic-like behaviour and promotes strategic cognitive performance in a rodent touchscreen task

Figure 1

Experimental design. (A) Study design. Sucrose consumption tests (SCTs) were conducted throughout the experiment to measure baseline sucrose intake, stress and drug effects (discriminating high vs low respond to treatment). Touchscreen testing included food reduction, pre-training, different paired-associates learning (dPAL) task acquisition and retention. Rats were euthanized and brain tissue was collected (X) 1–3 days after dPAL retention test. (B) Touchscreen pre-training. Passing criteria to move on to the next stage are indicated alongside the arrows. Peanut butter was added to the screen when the rat entered “must touch” or when performing ≤ 40 touches in the previous “must touch” session.

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