Figure 6
From: Discovery, optimization, and evaluation of non-bile acid FXR/TGR5 dual agonists
Concentration–response curves. (a) OCA FXR EC50 value; (b) INT-767 FXR EC50 value; (c) 20p FXR EC50 value; (d) 20q FXR EC50 value; (e) INT-767 TGR5 EC50 value; (f) 20p TGR5 EC50 value; (g) 20q TGR5 EC value; (h) Structures of 20p and 20q.
