Figure 9
From: Disentangling age-dependent DNA methylation: deterministic, stochastic, and nonlinear
Example of CpG probes for which Fano factor (the variability normalized to the average beta value) is age independent with a p value \(> 0.9\) in GSE87571 dataset. The top panel presents scatter plots for males: the methylation level (a), the variability (b), the Fano factor (c). (d)–(f) on the bottom panel present similar graphs for females. Curves represent the average level of methylation taken over a sliding window of 10 years for males (blue curves) and females (red curves). Black lines represent linear regression fits.
