Table 3 Associations between serum adiponectin levels and inflammation defined as CRP ≥ 7.8 mg/L (above of the median of its distribution) in the whole study population and in subgroups of patients categorized by comorbidity index according to univariate and multivariable logistic regression analyses.

From: Comorbidity burden may explain adiponectin’s paradox as a marker of increased mortality risk in hemodialysis patients

Variable

Univariate

Multivariable*

OR (95% conf. interval)

p

OR (95% conf. interval)

p

All patients (n = 261)

CRP ≥ 7.8 mg/L

    

 Per 1 mcg/ml↑

0.99 (0.99–1.00)

0.05

0.99 (0.98–1.00)

0.03

 ≥ 8.28 mcg/ml

0.63 (0.39–1.04)

0.07

0.53 (0.31–0.90)

0.02

Comorbidity index ≤ 4 (n = 142)

CRP ≥ 7.8 mg/L

    

 Per 1 mcg/ml↑

0.99 (0.99–1.01)

0.35

0.99 (0.98–1.00)

0.24

 ≥ 8.28 mcg/ml

0.70 (0.36–1.39)

0.31

0.61 (0.29–1.27)

0.19

Comorbidity index > 4 (n = 119)

CRP ≥ 7.8 mg/L

    

 Per 1 mcg/ml↑

0.99 (0.98–1.00)

0.04

0.99 (0.07–1.00)

0.04

 ≥ 8.28 mcg/ml

0.48 (0.23–1.02)

0.06

0.44 (0.20–0.96)

0.04

  1. CRP, C-reactive protein; OR, odds ratio; DM, diabetes mellitus.
  2. *Adjusted for age, sex, DM status, dialysis vintage, residual renal function, comorbidity index, smoking and Kt/V.
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