Figure 9
An interaction model illustrates how RGS7 degradation is Ate1-dependent and Ate1 knockout increases the level of RGS7. Since RGS7 competes with RGS11 (or other R7 RGS proteins) for binding with G\(\beta _5\) (or other R7 binding proteins) and increases the stability of G\(\beta _5\) through dimer formation, an increase in RGS7 can cause a decrease in RGS11 and/or an increase in G\(\beta _5\).
